Our core formulations harness the power of exosomes, PDRN, botanic extracts, and peptides to deliver advanced, science-based skincare solutions.

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ExosomesThe Future of Cellular Regeneration

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Exosomes - The Future of Cellular Regeneration

The exosomes used in SM DERMA’s products are derived from carefully selected human and plant stem cell conditioned media, processed through thorough sterilization and strict quality control. Each batch is precisely characterized at 155.0 ± 61.5 nm with a concentration of 7×10⁹ particles/ml, ensuring consistency and reliability. Clinically validated and supported by ongoing trials, our exosomes deliver high-performance regenerative benefits with proven effectiveness.

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PDRNGold Standard for Skin Regeneration

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PDRN – Gold Standard for Skin Regeneration

Our PDRN is sourced from premium French salmon DNA, recognized as the gold standard for skin rejuvenation and repair. Using advanced enzymatic hydrolysis and purification technology, we eliminate proteins, endotoxins, and impurities, achieving an exceptional purity of 97–99%. Clinically trusted and officially approved by the French Ministry of Health (HPDR) for medical-grade use, this ingredient ensures both safety and superior performance in our formulations.

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Collagen PeptidesTargeted Skin Communication Signals

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Collagen Peptides – Targeted Skin Communication Signals

Our collagen peptides are carefully engineered short chains of amino acids that act as powerful messengers, stimulating collagen synthesis, improving elasticity, and reducing visible wrinkles. Through advanced formulation and stability technology, SM DERMA ensures optimal bioavailability and synergy with other active ingredients. Clinically supported for anti-aging and skin-repair benefits, our collagen peptides provide targeted action for firmer, smoother, and healthier-looking skin.

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Botanical ExtractsNatural Power for Skin Balance

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Botanical Extracts – Natural Power for Skin Balance

SM DERMA integrates high-purity botanical extracts sourced from trusted plants known for their antioxidant, soothing, and revitalizing properties. Each extract is processed under strict quality control to preserve active compounds and maximize efficacy in skin regeneration and protection. By combining tradition with innovation, our botanical extracts provide natural balance, protection against environmental stress, and enhanced skin vitality. Main botanical sources: Licorice Root, Citrus, Aloe Vera, Centella Asiatica (Cica), Green Tea, Ginseng Root, Soybean, Coconut.

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PDRNGold Standard for Skin Regeneration

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PDRN – Gold Standard for Skin Regeneration

Our PDRN is sourced from premium French salmon DNA, recognized as the gold standard for skin rejuvenation and repair. Using advanced enzymatic hydrolysis and purification technology, we eliminate proteins, endotoxins, and impurities, achieving an exceptional purity of 97–99%. Clinically trusted and officially approved by the French Ministry of Health (HPDR) for medical-grade use, this ingredient ensures both safety and superior performance in our formulations.

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Botanical ExtractsNatural Power for Skin Balance

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Botanical Extracts – Natural Power for Skin Balance

SM DERMA integrates high-purity botanical extracts sourced from trusted plants known for their antioxidant, soothing, and revitalizing properties. Each extract is processed under strict quality control to preserve active compounds and maximize efficacy in skin regeneration and protection. By combining tradition with innovation, our botanical extracts provide natural balance, protection against environmental stress, and enhanced skin vitality. Main botanical sources: Licorice Root, Citrus, Aloe Vera, Centella Asiatica (Cica), Green Tea, Ginseng Root, Soybean, Coconut.